• Call
  • 0208 123 0703


Mysimba is a modified release tablet which has been approved in the UK for use alongside a reduced-calorie diet and increased physical activity. Mysimba has successfully shown many obese and overweight adults in the UK how to lose weight quickly by reducing appetite and food cravings.



What is Mysimba?

Mysimba is an effective weight loss medication used for the management of weight in adults over the age of 18 with a body mass index (BMI) of over 30, or over 27 if weight-related co-morbidities such as type 2 diabetes or controlled hypertension are a factor.

There are many reasons why people gain weight. Some of the most common among them include excessive hunger, difficulty managing portion sizes and stress or anxiety-related eating. Mysimba can help adults struggling with obesity to lose their excess weight quickly, effectively and safely.

Why Mysimba?

Mysimba is proven to be an effective weight loss treatment. Studies have documented that Mysimba can help you lose an average of 5% of your total body weight when taken in conjunction with a healthy eating regime. This compares to just a 1% loss through dieting alone. 42% of Mysimba users lost at least 5% of their total body weight, compared to just 17% of those not using Mysimba.

By reducing your overall weight, Mysimba can help to reduce the dangerous build up of fat around your waistline. This ring of fat is a contributing factor in many serious health conditions, including type 2 diabetes and cardiovascular issues.

Mysimba can also help to reduce LDL cholesterol, or ‘bad’ cholesterol. Diabetics using Mysimba have found improvements in their blood sugar control.

How it works

Mysimba contains two active ingredients. These are Naltrexone and Bupropion.

Both of these medicines work in the reward pathways of the brain in order to reduce feelings of hunger and alleviate food cravings. Naltrexone helps to curb cravings, having previously been prescribed to reduce alcohol dependence. Similarly, Bupropion helps to reduce appetite and has previously been used as an antidepressant and to help people stop smoking.

Although both Naltrexone and Bupropion have been used as medications before, Mysimba marks the first time they have been combined in a single weight loss treatment. This combination acts on parts of the brain which control food intake and energy balance, and control the pleasure associated with eating food.

How to Take Mysimba

Mysimba should always be taken as prescribed, alongside a reduced-calorie diet and an increase in physical activity. It must only be used by obese adults over the age of 18 to help with weight management.

The regular dosage of Mysimba is to start by taking one tablet each morning for one week. During the second week, one tablet can be taken in the morning and another tablet can be taken in the evening. For the third week, users can take two tablets in the morning and a single tablet in the evening. In week four, Mysimba dosage can increase to two tablets in the morning and two in the evening.

If you do not lose 5% of your total body weight within 16 weeks of using the weight loss treatment, consumption of Mysimba should be stopped.

Who can use Mysimba?

If you are an overweight adult over 18, Mysimba may be applicable to you as a weight loss treatment. It is not suitable for pregnant women, women trying to conceive or individuals with liver or kidney disease.

You should avoid Mysimba if you have experienced uncontrolled hypertension or seizure disorder in the past. You should also avoid the weight loss medication if you have a known central nervous system tumour or are experiencing alcohol withdrawal. Individuals with mental health or eating disorders should also avoid the use of Mysimba, including bipolar disorder, bulimia or anorexia nervosa. Those with a history of depression should use the medication with caution.

Side Effects

As is the case with all prescription medications, Mysimba can cause some side effects. Most users won’t experience any side effects, and for those that do these side effects will most likely be mild. Side effects sometimes associated with Mysimba include:

  • Insomnia and restlessness
  • Headaches
  • Anxiety
  • Dizziness
  • Hot flushes
  • Lack of concentration
  • Constipations
  • Palpitations
  • Muscular pain
  • Nausea

If you do experience side effects, please consult your pharmacist or GP.


The use of Mysimba should be discontinued if you have not lost at least 5% of your initial body weight after 16 weeks of using the treatment alongside diet and exercise. You should also stop using this weight loss treatment if you experience any unusual side effects.

Do not use Mysimba if you have an allergy to any of the active ingredients. Whilst taking Mysimba, it is advised that you get your blood pressure checked regularly.

Reviews for Mysimba

100% of customers liked this medication (1 reviews)

Date Rating Comment
20-Dec-2017 Excellent medication as appetite suppressant. It’s quite expensive. But for sure you won’t regret buying it.

View all Reviews for Mysimba


Medication Quantity Price
Mysimba 112 £224.99

Patient Information

Always read the patient information leaflet before commencing treatment. The patient information can be found here .

Mysimba is rated 10 / 10 based on 1 independent customer reviews taken by Feefo.
Product Rating:
1 reviews

Estimated delivery

Order in the next to receive your order on the following days:

Friday 16 Nov by 10:30AM with UPS Express

Friday 16 Nov - Monday 19 Nov with Royal Mail Signed For™

Friday 16 Nov with Royal Mail Special Delivery™

Friday 16 Nov with UPS Next Day Local Collection

* Please note that delivery estimates don't take public holidays into account, so your delivery may be later if there is a public holiday between today and your estimated delivery date.

Recent Blog

Learn more about common health problems affecting many of us every day.

Post: Mon 17 September 2018 by Tim Deakin

Research Reveals That Lack of Exercise Puts One in Four People at Risk

The World Health Organisation is shining a light on the importance of regular fitness

Read More
Post: Wed 18 April 2018 by Tim Deakin

What More Can We Do for Mental Health?

Research shows that there is still a long way to go when it comes to mental health awareness and support

Read More
Post: Mon 29 January 2018 by Tim Deakin

Ready to Ditch Your New Year’s Resolution. Read This!

Don’t be a six-week dropout: how to stick to the new leaf you turned over in January

Read More


At Express Pharmacy, we take customer service seriously and we are proud of the great feedback we've received from our customers.


Excellent medication as appetite suppressant. It’s quite expensive. But for sure you won’t regret buying it.

Read More

Next Day Delivery

Free Consultation

Free Prescription

Three easy steps
to your medication

Select Treatment

Select the treatment your require
from the homepage,
or select from the menu at the top.

Free Consultation

Complete a free online medical questionnaire to see if this treatment is suitable for you.


Pay for your treatment using our secure card payment system.