Due to the current circumstances we are unable to take any new orders for the time being



Xenical, otherwise known as orlistat in its generic form, works by reducing the amount of fat absorbed during digestion. Orlistat is an effective method of weight loss for many obese and overweight people in the UK.

This product is currently unavailable
Clock Icon

Order in the next to receive your order on the following days:

Type Delivery date Cost
DPD Next Day Mon 30 May - Tue 31 May £5.00
Royal Mail Tracked 48 Sun 29 May - Thu 02 Jun £3.00
Royal Mail Special Delivery™ Sat 28 May £5.95

What is Xenical?

Xenical (Orlistat 120mg) is a prescription medication that can help in the treatment of weight-loss. Xenical prevents your body from absorbing the fat from the food you eat. By reducing the amount of fat which is absorbed, Xenical can help you to lose weight more easily.

Why Xenical?

In clinical studies, almost two-thirds of people treated with Xenical weight loss pills successfully lost at least 5% of their body weight after 2 years, when used alongside a healthy diet. In comparison, only half of the people treated with diet alone managed to lose 5% of their weight.

Using Xenical to support weight loss in conjunction with a healthy diet can lower a number of weight-related health risks. Studies show that weight loss with Xenical can:

  • Decrease total and LDL cholesterol (level of low-density lipoprotein – also known as bad cholesterol)
  • Improve your ratio of bad to good cholesterol (LDL/HDL cholesterol)
  • Reduce blood pressure
  • Reduce levels of insulin. Insulin is the hormone that allows glucose or sugar to enter the body's cells — high levels are associated with coronary heart disease
  • Reduce the risk or delay the progression to type 2 diabetes in patients

How does Xenical help you lose weight?

Xenical works within the digestive system, inhibiting the absorption of fat into the body. Xenical attaches itself to the enzymes in your digestive system (lipases) and blocks them from breaking down up to a third of the fat you have eaten during your meal.

This undigested fat cannot be absorbed and is eventually excreted from your body. This allows Xenical to act as an effective weight loss treatment when used in conjunction with a healthy, low calorie diet.

How to Take Xenical

The recommended dose of Xenical is one 120-mg capsule by mouth with liquid alongside each main meal containing fat.

You should take Xenical up to three times a day in conjunction with a reduced-calorie diet. Each time you take Xenical, your nutritionally balanced meal should contain no more than about 30% of calories from fat. You should evenly divide your daily intake of fat, carbohydrates and protein over three main meals.

Take Xenical during meals or up to 1 hour after a meal. If you occasionally miss a meal or have a meal without fat, you can omit your dose of Xenical. Doses above 120 mg three times daily have not been shown to provide an additional weight-loss benefit.


When you start taking Xenical you will be given a weight loss target for the first 3 months. This target is 5% of your total body weight. If you succeed in losing 5% of your weight, you will be eligible to continue taking Xenical. Pharmacists can supply Xenical for up to two years.

Each time Xenical is supplied you will need to supply your pharmacist with your current weight. If your weight goes up at all within a three month period, Xenical will need to be stopped. If you lose enough weight for your BMI to fall below 28, Xenical can no longer be supplied. This is because a BMI of 30 is the minimum value which indicates obesity.

Side Effects

Like all prescription medications, Xenical carries a small risk of side effects. However, side effects of Xenical are usually mild and are not experienced by all people.

Common side-effects of this weight loss medication include:

  • Headache
  • Abdominal pain or discomfort
  • Urgent or frequent need to open bowels
  • Flatulence with discharge
  • Oily discharge
  • Oily, liquid or fatty stools

Individuals with type 2 diabetes may experience low blood sugar levels. Reducing the amount of fat in your diet can help reduce any digestive side effects of Xenical.

Because Xenical works by altering your body's fat absorption, some fat-soluble vitamins can be affected. You should take a daily multivitamin supplement that contains vitamins A, D, E and K and beta carotene once a day at least 2 hours before or after taking Xenical, such as at bedtime.


Individuals who may be unsuitable for the use of Xenical include:

  • Pregnant women and breastfeeding women
  • Those with an allergy to orlistat
  • People with thyroid disorders
  • Sufferers of cholestasis (gallbladder problems)
  • People with kidney stones or other kidney problems
  • People with eating disorders

For more information, refer to the patient leaflet included with the medication.


How much weight can you lose with Xenical?

In clinical studies, almost two-thirds of people treated with Xenical weight loss pills successfully lost at least 5% of their body weight after 2 years (when used alongside a healthy diet).

How do you take Xenical?

You should take Xenical up to three times a day, alongside a reduced-calorie diet. Each time you take Xenical, your meal should contain no more than about 30% of calories from fat. If you miss a meal or have a meal without fat, you do not need to take a dose. Please see the ‘how to use’ tab for more guidance.

Does Xenical work immediately?

Xenical starts to work as soon as you take it. If taken as directed, you should start to see results within two weeks.

How long can you use Xenical for?

If you do not lose at least 5% of your weight after 3 months, stop taking it. You should not take Xenical for more than 6 months.

Do you gain weight back after Xenical?

You are more likely to keep the weight off after Xenical if you stick to a balanced diet and healthy lifestyle.

Can you drink alcohol on Xenical?

Xenical does not interact with alcohol, meaning it is safe to drink alongside the weight loss treatment. However, it’s important to remember that alcohol is highly calorific and may hinder your journey.

What are the side effects of Xenical?

Xenical carries the risk of small side effects. This includes headaches, abdominal pain, and changes in bowel movements. Please see the ‘side effects’ tab for more information.

Xenical vs. other weight loss methods

There are typically two different kinds of weight loss medications. Some medications are appetite suppressants and others work within the digestive system to prevent fat absorption.

While there are hundreds of weight loss products on the market, it is crucial that individuals looking for medication only ever order prescriptions from reputable, regulated pharmacies. Purchasing from other online sources can be extremely dangerous.

Can I buy Xenical online?

Xenical is a prescription medication, meaning you must complete our online assessment before you can purchase it.


Medication Quantity Price

Patient Information

Before taking any medication, it is important to read the Patient Information Leaflet. You can find the information by searching for your treatment on Medicines.org.uk.

If you have any questions about your treatment please refer to Medicines.org.uk or contact us.

Xenical Patient Information Leaflet

Latest product reviews from feefo


Does absolutely what it promises.

Read More


Good product would recommend

Read More


Great product Happy with purchase

Read More

Related guides and articles

Get your medication in three simple steps

Mouse pointer icon

1. Select treatment

Select your treatment with help from our A-Z guide or navigation bar.

2 people talking icon

2. Free consultation

Complete our free consultation. Complete privacy guaranteed.

Package icon

3. Discreet delivery

Pay for your treatment & enjoy discreet delivery. Next day delivery available.